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2026 Glamour Beauty & Wellness Award Winner: Best Acne Treatment

A fast-acting, precision spot treatment to clear acne and allow it to heal overnight – without irritation. 5% medicinal colloidal sulfur treats blackheads and whiteheads, absorbs excess sebum, and reduces acne bacteria to prevent repeat breakouts. Natural kaolin and bentonite draw out clogging impurities, as niacinamide and a barrier-building blend of lilac, hibiscus, lavender, gotu kola, oregano and thyme target post-acne dark spots and leave skin soothed. Skin is clearer, smoother, calmer in the morning. Free of problematic benzoyl peroxide.

from Glamour: "its clay and sulfur formula dries down into a thin, protective layer across your blemish…my pimples are noticeably smaller and less irritated [by morning]" 
– T.K., Glamour editor

Spot Defy

Regular price $38.00
Unit price
per 

5% sulfur overnight acne spot treatment to clear active blemishes

Skin Types: Sensitive, Acne Prone

Skin Concerns: Breakouts, Clogged + Enlarged Pores, Rough Texture, Dull Skin

Free shipping on orders over $35

90-day free returns

Google Top Quality Store

2026 Glamour Beauty & Wellness Award Winner: Best Acne Treatment

A fast-acting, precision spot treatment to clear acne and allow it to heal overnight – without irritation. 5% medicinal colloidal sulfur treats blackheads and whiteheads, absorbs excess sebum, and reduces acne bacteria to prevent repeat breakouts. Natural kaolin and bentonite draw out clogging impurities, as niacinamide and a barrier-building blend of lilac, hibiscus, lavender, gotu kola, oregano and thyme target post-acne dark spots and leave skin soothed. Skin is clearer, smoother, calmer in the morning. Free of problematic benzoyl peroxide.

from Glamour: "its clay and sulfur formula dries down into a thin, protective layer across your blemish…my pimples are noticeably smaller and less irritated [by morning]" 
– T.K., Glamour editor

Reviews

Overall rating: 4.609375 / 5 from 64 reviews.

AI Generated Review Summary

Spot Defy is a fast-acting spot treatment that effectively clears acne and reduces blemishes overnight. Customers appreciate its gentle, non-irritating formula, which includes natural ingredients like kaolin and bentonite. The product is praised for its ability to soothe skin and leave it looking clearer and healthier.

Summary topics

  • Impurity Removal: 19%
  • Acne Clearing: 16%
  • Skin Comfort: 16%
  • Ingredient Quality: 14%
  • Overnight Results: 16%

Review topics: ["ingredients","irritation","results","use","improvement","feels","spots","difference","texture","consistency","packaging","works","formula","skin","looks","effect","acne","breakouts","reduction","treatment","pimples","container","acne spot treatment","blemishes","cleared","bioelements","solution","clay","mask","take"].

Review highlights

  • "Overnight, it works to reduce blackheads, and whiteheads, and by morning, my skin looks clearer and feels smoother."Amina
  • "Overall, it's a reliable and gentle option for overnight acne treatment."Sofia
  • "My skin looks clearer and healthier overall, and I couldn't be happier with the results."Mya l.

Reviews

Amazing Product

"I have had acne issues for over 50 years. Spot defy is amazing! It clears up any pimples I do get in a very short time. My skin has never looked better."

Kay H. (5/5)

I miss break out control

"Picked this up because it’s supposed to be the replacement for break out control. I still miss break out control it worked so much better… this isn’t bad but I know what their true potential is :("

Karen N. (3/5)

Bring BACK BREAKOUT CONTROL!!!! Please

"PLEASE BRING BACK BREAKOUT CONTROL!!!! Please, nothing compares to it!!"

Lorena F. (3/5)

Please

"Bring back breakout control please"

Laurie (5/5)

Please bring back amino mask

"Sad that they discontinued the amino mask, and this is only available with sulfur. My skin loved the amino mask."

Fah F. (3/5)

Happily surprised with this vs. breakout control

"I was hesitant about this working for me. I used the product out before this, breakout control, which I loved. I was pleasantly surprised that this works great! I think this product will go a lot longer than the breakout control as well but I'll definitely buy again when needed."

Renee K. (5/5)

Not as effective as Breakout Control.

"I bought this product after the Breakout Control was discontinued. It definitely has a funky smell to it, but I was willing to overlook that if it worked well. It did not. I found that it often flaked off of my larger blemishes so didn’t actually stay put over night to treat my acne. Unlike the Breakout Control, this product cannot be worn under makeup, which is a big downside for me. Overall I am pretty unhappy with this product and am wishing that Bioelements would bring back the Breakout Control."

Nichole C. (2/5)

Not a fan of clay

"So the product works but I’m not a huge fan. The clay I don’t think is what I like for a product I sleep in. The only reason it is not getting 5 stars."

lizz D. (4/5)

Great product thanks for the improvement

"Love this new version of breakout control. Way better!"

Diana B. (5/5)

My new favorite product

"I love this product it really works well, one of my new favorites"

Robin H. (5/5)

Q&A

Will this work/recommended for enlarged pores on 50+ skin? I have combination skin and looking to improve enlarged pores as a result of aging and hormonal skin. Nose, chin and forehead.
This formula is designed to clear active acne breakouts. While it will also target clogged pores, check out our Peel Breaker formula as well for this skin concern: https://www.bioelements.com/collections/clogged-pores-enlarged-pores/products/peel-breaker

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